Children's epilepsy resource for Clinicians

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Introducing a New Drug


  • When introducing a new drug, review the history to see what has been useful in the past.
  • When adding a second drug, you may commence weaning of the first drug immediately to achieve monotherapy, or you may try a defined period of overlap to determine if the combination is successful, provided both drugs are tolerated. The approach depends on the individual situation.
  • Benzodiazepines and phenobarbitone weaning regimens need to be gradual.






This page was created in March 2012. It was last reviewed in December 2017.